MARBIONC ELISA Kits are now available through SeaTox Research and can be purchased following the link here or reaching out to UNCW for a direct referral.
Trivial Name: PbTx-Carboxylic Acid, Brevetoxin B5, BTX-B5
CAS Registry Number: 155173-05-0
Source Organism: Karenia brevis
Formula: C50H70O15
Exact Mass: 910.4707
Formula Weight: 911.2
Production Method: Semi synthetic derivative of natural product
Storage/Shipping Conditions: Material is packaged in glass vials under vacuum and is stable during shipment and under normal handling procedures. If prolonged storage is required, keep the material in a tightly closed container at -20°C until needed
Mode of action:
Brevetoxins are known to bind to site 5 of voltage-gated sodium channels in nerve cells, leading to channel activation. This leads to disruption of normal neurological processes and causes the illness clinically described as neurotoxic shellfish poisoning (NSP).1 PbTx-Carboxylic Acid contains a brevetoxin B backbone.